|  Read this recommendation medwireNews: The British Society for Rheumatology has issued updated guidelines for the diagnosis and treatment of giant cell arteritis (GCA). 2016;75:1583-94.) medwireNews: EULAR has released updated recommendations for the management of large vessel vasculitis, including giant cell arteritis (GCA) and Takayasu arteritis.. Internist (Berl). T +41 44 716 30 30 As new-onset headache is one of the principal symptoms of cranial GCA, neurologists often assess (and indeed may manage) people with this condition, in isolation from rheumatology. High dose glucocorticoid therapy (40-60 mg/day prednisone-equivalent) should be initiated immediately for induction of remission in active giant cell arteritis (GCA) or Takayasu arteritis (TAK). Go to Recommendations EULAR Feedback on the EU Pharmaceuticals Strategy Roadmap. 4. See slide deck, David T Felson Josef S Smolen, George Wells, Bin Zhang, Lilian HD van Tuyl, Julia Funovits, Daniel Aletaha, Cornelia F Allaart, Joan Bathon, Stefano Bombardieri, Peter Brooks, Andrew Brown, Marco Matucci-Cerinic, Hyon Choi, Bernard Combe, Maarten de Wit, Maxime Dougados, Paul Emery, Daniel Furst, Juan Gomez-Reino, Gillian Hawker, Edward Keystone, Dinesh Khanna, John Kirwan Tore K. Kvien, Robert Landewé, Joachim Listing, Kaleb Michaud, Emilio Martin-Mola, Pamela Montie, Theodore Pincus, Pamela Richards, Jeffrey N Siegel, Lee S Simon, Tuulikki Sokka-Isler, Vibeke Strand, Peter Tugwell, Alan Tyndall, Desirée van der Heijde, Suzan Verstappen, Barbara White, Frederick Wolfe, Angela Zink, Maarten Boers Non-biological glucocorticoid-sparing agents should be given in combination with glucocorticoids in all patients with TAK and biological agents may be used in refractory or relapsing patients. 2016;43:97-120.) EULAR Recommendations 2020. EULAR Recommendations: Recommendations and initiatives The EULAR Standing Committees regularly establish and publish recommendations for the treatment of various rheumatic disorders. COVID-19 is an emerging, rapidly evolving situation. Ann Rheum Dis 2010;69:1589-1595 doi:10.1136/ard.2010.130310 eCollection 2020. 5 Equally, a low pre-test probability and negative imaging is felt to be sufficient to exclude the diagnosis, though in all other cases, further efforts should be made towards establishing a definitive diagnosis, such as a … http://ard.bmj.com/content/75/9/1583.full?sid=55d485e0-a8c0-4f43-aa46-0ffe9fa81269. Overview BSR's 'gold standard' clinical guidelines support evidence-based clinical practice in rheumatology. See slide deck, W Zhang, M Doherty, T Bardin, V Barskova, P-A Guerne, T L Jansen, B F Leeb, F Perez-Ruiz, J Pimentao, L Punzi, P Richette, F Sivera, T Uhlig, I Watt, E Pascual Published Online First 13 April 2010 EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides The recommendations for the guidelines are set out in points 1 to 9. EULAR Recommendations: Recommendations for management. EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria 2019 Sep 16;5(2):e001003. This site needs JavaScript to work properly. PV received a grant for conducting an RCT in GCA from Roche. Part II: Final classification criteria Ann Rheum Dis 2011;70:404-413 doi:10.1136/ard.2011.149765 Publication Online: 2 March 2011 This paper focuses on the data relevant to giant cell arteritis (GCA). CD received and grant from Celgene and speaker fees and/or consultancies from Abbvie, BMS, Lilly, MSD, Pfizer, Novartis, UCB, Roche and Sanofi. 2020 Nov 29;11:2040622320975233. doi: 10.1177/2040622320975233. ... 2018 EULAR recommendations for a core data set to support observational research and clinical care in … 2020 Dec 10;22(1):285. doi: 10.1186/s13075-020-02365-y. Gunasekera SN, Madurapperuma C, Weerasooriya N, Karunathilake H, Jayanaga A. BMC Rheumatol. Association between acute phase reactants, interleukin-6, tumor necrosis factor-α, and disease activity in Takayasu's arteritis patients. Part I: Overall methodology and clinical characterisation Most occurrences of blindness or stroke happen either before treatment or during the first week of treatment [3]. Frank van den Hoogen, Dinesh Khanna, Jaap Fransen, Sindhu R Johnson, Murray Baron, Alan Tyndall, Marco Matucci-Cerinic, Raymond P Naden, Thomas A Medsger, Jr, Patricia E Carreira, Gabriela Riemekasten, Philip J Clements, Christopher P Denton, Oliver Distler, Yannick Allanore, Daniel E Furst, Armando Gabrielli, Maureen D Mayes, Jacob M van Laar, James R Seibold,, Laszlo Czirjak, Virginia D Steen, Murat Inanc, Otylia Kowal-Bielecka, Ulf Müller-Ladner, Gabriele Valentini, Douglas J Veale, Madelon C Vonk, Ulrich A Walker, Lorinda Chung, David H Collier, Mary Ellen Csuka, Barri J Fessler, Serena Guiducci, Ariane Herrick, Vivien M Hsu, Sergio Jimenez, Bashar Kahaleh, Peter A Merkel, Stanislav Sierakowski, Richard M Silver, Robert W Simms, EULAR large vessel guidelines say if refractory GCA consider addition of Tocilizumab or MTX to steroids. Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis: focus on giant cell arteritis. eCollection 2019. CT received a grant from BMS and speaker fees and/or consultancies from Abbvie, BMS, Pfizer and Roche. Sarah Mackie (University of Leeds, UK) and co-authors say that these recommendations constitute “a major revision to the 2010 British Society for Rheumatology guideline for the management of GCA” in light of new evidence regarding diagnosis and treatment. Read this recommendation, L Gossec, M Dougados, N Rincheval, A Balanescu, D T Boumpas, S Canadelo, L Carmona, J-P Daurès, M de Wit, B A C Dijkmans, M Englbrecht, Z Gunendi, T Heiberg, J R Kirwan, E M Mola, M Matucci-Cerinic, K Otsa, G Schett, T Sokka, G A Wells, G J Aanerud, A Celano, A Dudkin, C Hernandez, K Koutsogianni, F N Akca, A-M Petre, P Richards, M Scholte-Voshaar, G Von Krause, T K Kvien 2019 Oct;124(10):965-972. doi: 10.1007/s11547-019-01058-0. Published Online First 17 May 2006 EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis WS received a grant from Roche and speaker fees and consultancies from Chugai, GSG, Novartis, Roche and Sanofi. Ann Rheum Dis. For this statement the group extrapolated the data from randomised controlled trials,29, 31 and took clinical experience, national PMR guidelines,28–30 as well as current ACR and/or EULAR recommendations on the use of GCs in rheumatic diseases into account.32–35 In addition, there is incontrovertible external evidence of harm from long-term large doses of GCs32–35 and lack of … Aortic imaging should be considered in giant cell arteritis, especially in patients with an aortic insufficiency murmur,73 because subclinical involvement is common and may progress to form aneurysm or dissection in 9%–18% of patients.14, 73 – 76 In symptomatic patients, the presence of normal inflammatory markers should raise suspicion of an alternative diagnosis. This page lists the EULAR Recommendations for management dating back to the year 2000. The panel strongly recommends using the minimum effective individualised duration of GC therapy in PMR patients The panel conditionally recommends using the minimum effective GC dose within a range of 12.5–25 mg prednisone equivalent daily as the initial treatment of PMR. EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis We have updated the recommendations for the management of LVV to facilitate the translation of current scientific evidence and expert opinion into better management and improved outcome of patients in clinical practice. Clin Med (Lond). Therefore, EULAR and national guidelines recommend adjunctive GC-sparing therapies for relapsing GCA patients and/or patients who have developed or have an increased risk of developing such GC-related … Ann Rheum Dis 2010;69; 69: 790 - 797. The European League Against Rheumatism has updated treatment guidelines for the management of large vessel vasculitis. Epub 2008 Apr 15. HHS Giant cell arteritis (GCA) is a chronic vasculitis characterized by granulomatous inflammation in the walls of medium and large arteries. 2018 May;77(5):636-643. doi: 10.1136/annrheumdis-2017-212649. Ann Rheum Dis, Dec 2003; 62: 1189 - 1194. We recommend adjunctive therapy in selected patients with GCA (refractory or relapsing disease, presence of an increased risk for glucocorticoid-related adverse events or complications) using tocilizumab. EULAR response criteria for polymyalgia rheumatica: results of an initiative of the European Collaborating Polymyalgia Rheumatica Group (subcommittee of ESCISIT) http://www.jrheum.org/content/43/1/97.long BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis. [Large-vessel vasculitis-giant cell and Takayasu arteritis]. Methods: 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative NLM Authors Mohammad Bardi 1 , Andreas P … Using EULAR standardised operating procedures for EULAR-endorsed recommendations, the EULAR task force undertook a systematic literature review and sought opinion from 20 experts from 13 countries. Published Online First 17 September 2009 Read this recommendation, W Zhang, M Doherty, G Peat, S MA Bierma-Zeinstra, N K Arden, B Bresnihan, G Herrero-Beaumont, S Kirschner, B F Leeb, L S Lohmander, B Mazières, K Pavelka, L Punzi, A K So, T Tuncer, I Watt and J W Bijlsma Recommendation 1: in patients with suspected GCA, an early imaging test is recommended to complement the clinical criteria for diagnosing GCA, assuming high expertise and prompt availability of the imaging technique. Three overarching principles and 10 recommendations were formulated. 2009 Mar;68(3):318-23. doi: 10.1136/ard.2008.088351. Please enable it to take advantage of the complete set of features! Report of a task force of the Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT) Methotrexate may be used as an alternative. Objective To collect available evidence on management of large vessel vasculitis to inform the 2018 update of the EULAR management recommendations. Ann Rheum Dis, Jan 2009; 68: 8 - 17 Published Online First 4 February 2008 Giant cell arteritis (GCA) represents the most common form of primary systemic vasculitis and is frequently associated with comorbidities related to the disease itself or induced by the treatment. Read this recommendation, Daniel Aletaha, Tuhina Neogi, Alan J Silman, Julia Funovits, David T Felson, Clifton O Bingham III, Neal S Birnbaum, Gerd R Burmester, Vivian P Bykerk, Marc D Cohen, Bernard Combe, Karen H Costenbader, Maxime Dougados, Paul Emery, Gianfranco Ferraccioli, Johanna MW Hazes, Kathryn Hobbs, Tom WJ Huizinga, Arthur Kavanaugh, Jonathan Kay, Tore K Kvien, Timothy Laing, Philip Mease, Henri A Ménard, Larry W Moreland, Raymond L Naden, Theodore Pincus, Josef S Smolen, Ewa Stanislawska-Biernat, Deborah Symmons, Paul P Tak, Katherine S Upchurch, JiYí Vencovský, Frederick Wolfe, Gillian Hawker Giant cell arteritis (GCA) presents to all specialties due to its early non-specific initial symptoms. Read this recommendation, Nicolino Ruperto, Seza Ozen, Angela Pistorio, Pavla Dolezalova, Paul Brogan, David A Cabral, Ruben Cuttica, Raju Khubchandani, Daniel J Lovell, Kathleen M O'Neil, Pierre Quartier, Angelo Ravelli, Silvia M Iusan, Giovanni Filocamo, Claudia Saad Magalhães, Erbil Unsal, Sheila Oliveira, Claudia Bracaglia, Arvind Bagga, Valda Stanevicha, Silvia Magni Manzoni, Polyxeni Pratsidou, Loredana Lepore, Graciela Espada, Isabelle Kone Paut, Francesco Zulian, Patrizia Barone, Zelal Bircan, Maria del Rocio Maldonado, Ricardo Russo, Iris Vilca, Kjell Tullus, Rolando Cimaz, Gerd Horneff, Jordi Anton, Stella Garay, Susan Nielsen, Giancarlo Barbano, Alberto Martini, for the Paediatric Rheumatology International Trials Organisation (PRINTO) Contact. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Ann Rheum Dis 2010;69:1580-1588 doi:10.1136/ard.2010.138461 Ann Rheum Dis, Jul 2006; 65: 936 - 941. Epub 2018 Jan 22. Visual symptoms (including diplopia). Yip A, Jernberg ET, Bardi M, Geiger J, Lohne F, Schmidt WA, Myklebust G, Diamantopoulos AP. As GCA is considered a medical emergency, it is treated at the point of diagnosis by clinicians in primary and secondary care who have a wide variety of clinical backgrounds. We recommend that a suspected diagnosis of LVV should be confirmed by imaging or histology. Read this recommendation, Neil Basu, Richard Watts, Ingeborg Bajema, Bo Baslund, Thorsten Bley, Maarten Boers, Paul Brogan, Len Calabrese, Maria C Cid, Jan Willem Cohen-Tervaert, Luis Felipe Flores-Suarez, Shouichi Fujimoto, Kirsten de Groot, Loic Guillevin, Gulen Hatemi, Thomas Hauser, David Jayne, Charles Jennette, Cees G M Kallenberg, Shigeto Kobayashi, Mark A Little, Alfred Mahr, John McLaren, Peter A Merkel, Seza Ozen, Xavier Puechal, Niels Rasmussen, Alan Salama, Carlo Salvarani, Caroline Savage, David G I Scott, Mårten Segelmark, Ulrich Specks, Cord Sunderköetter, Kazuo Suzuki, Vladimir Tesar, Allan Wiik, Hasan Yazici, Raashid Luqmani 2 This thorough review of evidence published on the diagnosis, monitoring and treatment of GCA included studies published through … Read this recommendation, W Zhang, M Doherty, B F Leeb, L Alekseeva, N K Arden, J W Bijlsma, F Dincer, K Dziedzic, H J Hauselmann, P Kaklamanis, M Kloppenburg, L S Lohmander, E Maheu, M Martín-Mola, K Pavelka, L Punzi, S Reiter, J Smolen, G Verbruggen, I Watt and I Zimmermann-Górska Ann Rheum Dis Published Online First: 6 May 2010 doi:10.1136/ard.2009.119032 Scalp tenderness. Sara Monti, MD, a rheumatologist at Fondazione IRCCS Policlinico San Matteo, Italy, and colleagues performed the literature reviews that support the 2018 update of the EULAR recommendations on the management of large vessel vasculitis. Irreversible blindness is the most common serious consequence. The implementation of a fast-track approach to diagnosis … Among the changes, the task force no longer recommends the routine use of antiplatelet or anticoagulant therapy. Complications of GCA are largely prevented by treatment with adequate doses of corticosteroids and include: Vision loss. Constitutional s… An update on the general management approach to common vasculitides. Whereas in TAkayasu's you should start with immunosuppressive + steroids SP0192 #EULAR2019 @RheumNow pic.twitter.com/Sn1j5Pqzgu — Janet Pope (@Janetbirdope) June 15, 2019 Ann Rheum Dis 2012;71:484-492 doi:10.1136/annrheumdis-2011-200329 Our guidelines grow out of the collaborative efforts of many members and non-members, specialists and generalists, patients and carers. The original recommendations advised TAB in every case of suspected GCA.1 Since then, a large amount of good-quality data demonstrated that imaging and biopsy have similar diagnostic value if assessors are proficient in these techniques.2 13 The recently published EULAR recommendations for the use of imaging in LVV in clinical practice contain comprehensive advice regarding when and how … These guidelines form an update of the 2009 EULAR recommendations, and aim “to facilitate the translation of current scientific evidence and expert opinion into better management and improved outcome of patients in clinical practice,” say … Background: Contacts, Classification criteria/response criteria, Recommendations for conducting/reporting clinical trials, PARE (People with Arthritis and Rheumatism), EULAR On-line Course on Rheumatic Diseases, EULAR On-line Course on Connective Tissue Diseases, EULAR On-line Course on Systemic Sclerosis, EULAR On-line Introductory Ultrasound Course, EULAR / PReS On-line Course in Paediatric Rheumatology, EULAR On-line Course for Health Professionals, Educational visit programme for health professionals, Knowledge transfer programme for people with arthritis/rheumatism, Employment, social affairs and disability. Particular attention should be paid to the predictive features of ischaemic neuro-ophthalmic complications (C). Read this recommendation, Seestrasse 240 2019 Oct;60(10):1059-1073. doi: 10.1007/s00108-019-00666-2. EULAR guidelines now recommend that where a high pre-test probability for GCA exists and high quality imaging findings support that diagnosis, there is no need to perform further tests. Our updated guideline on its treatment ensures clinicians have the latest information about diagnosis and treatment, bringing the latest peer-reviewed evidence up-to-date and supporting clinicians in providing the best treatment for people with this disease. In the latest EULAR guidelines for the use of imaging in large-vessel vasculitis, CT and PET were not recommended for the evaluation of cranial GCA , mainly due to insufficient spatial resolution of these imaging modalities and high fluorodeoxyglucose (FDG) uptake in the brain during PET obscuring the assessment of temporal arteries. Results: We identified 287 eligible articles (122 studies focused on diagnosis/monitoring, 165 on treatment). 2020 Nov;20(6):572-579. doi: 10.7861/clinmed.2020-0747. The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Methodological Report Phase I In recent decades, clinical trials have delivered considerable evidence to underpin optimal diagnostic and therapeutic approaches. EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI): Development of a consensus systemic disease activity index in primary Sjögren's syndrome Ann Rheum Dis 2011;70:563-570 Published Online First: 7 January 2011 F +41 44 716 30 39 Part I: Overall methodology and clinical characterisation Ann Rheum Dis 2010;69; 69: 790 - 797. Ann Rheum Dis 2010;69:1744-1750 doi:10.1136/ard.2009.119032 Published Online First: 6 May 2010 Large vessel vasculitis (LVV) is the most common form of primary vasculitis comprising of giant cell arteritis (GCA), Takayasu's arteritis (TAK) and idiopathic aortitis. FB received grants from Horizon and Mundipharma and speaker fees and/or consultancies from Horizon, Mundipharma, Roche and Sanofi. Ann Rheum Dis doi:10.1136/annrheumdis-2012-202779 EULAR evidence based recommendations for gout. This article provides a brief overview of PSV in adults, focusing on the latest updates and recommendations for … In the UK population, incidence is about 2.2 per 10,000 person years. Published Online First 1 December 2005 (Rheumatolog… ... 2018 EULAR recommendations for a core data set to support observational research and clinical care in giant cell … The British Society of Rheumatology, which has been accredited by the National Institute for Health and Care … Seestrasse 240 CH 8802 Kilchberg (Zürich) Switzerland T +41 44 716 30 30 F +41 44 716 30 39 Contacts Read this recommendation We no longer recommend the routine use of antiplatelet or anticoagulant therapy for treatment of LVV unless it is indicated for other reasons. 2. Many patients with GCA have inflammation of the aorta and its proximal branches (extracranial large-ve…  |  Read the latest: - EULAR provisional recommendations for the management of rheumatic and musculoskeletal diseases in the context of SARS-CoV-2 - EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update. 2 nd speaker: Dr. Peter Lanyon (UK; BSR) – BSR Guidelines on diagnosis and treatment of giant cell arteritis (2019) 3 rd speaker: Dr. Bernhard Hellmich (EULAR; Germany) – 2018 Update of the EULAR recommendations for the management of large vessel vasculitis SM received speaker fees and consultancies from Roche and Chugai. Primary systemic vasculitides (PSV) are multisystem diseases associated with high morbidity and mortality, particularly if not treated in a timely manner. Giant cell arteritis (GCA) is a common form of vasculitis in people aged 50 years or older. Read this recommendation, Neil Basu, Richard Watts, Ingeborg Bajema, Bo Baslund, Thorsten Bley, Maarten Boers, Paul Brogan, Len Calabrese, Maria C Cid, Jan Willem Cohen-Tervaert, Luis Felipe Flores-Suarez, Shouichi Fujimoto, Kirsten de Groot, Loic Guillevin, Gulen Hatemi, Thomas Hauser, David Jayne, Charles Jennette, Cees G M Kallenberg, Shigeto Kobayashi, Mark A Little, Alfred Mahr, John McLaren, Peter A Merkel, Seza Ozen, Xavier Puechal, Niels Rasmussen, Alan Salama, Carlo Salvarani, Caroline Savage, David G I Scott, Mårten Segelmark, Ulrich Specks, Cord Sunderköetter, Kazuo Suzuki, Vladimir Tesar, Allan Wiik, Hasan Yazici, Raashid Luqmani EULAR/EFORT Recommendations for the diagnosis and initial management of patients with acute or recent onset swelling of the knee © Author(s) (or their employer(s)) 2020. 2020 Dec 10;4(1):66. doi: 10.1186/s41927-020-00166-z. Conclusions: Since the publication of the European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) in 2009, several relevant randomised clinical trials and cohort analyses have been published, which have the potential to change clinical care and therefore supporting the need to update the original recommendations. CH 8802 Kilchberg (Zürich) Switzerland GCA is therefore a medical emergency requiring immediate treatment. GCA, or temporal arteritis, is a large-vessel vasculitis affecting older people [1]. 5. EULAR Updates Guidelines for Large Vessel Vasculitis. A rare presentation of Takayasu's arteritis- unilateral finger clubbing - case report. 2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative doi: 10.1136/rmdopen-2019-001003. Published by BMJ. See slide deck, Julia Funovits, Daniel Aletaha, Vivian Bykerk, Bernard Combe, Maxime Dougados, Paul Emery, David Felson, Gillian Hawker, Joanna M Hazes, Tom Huizinga, Jonathan Kay, Tore K Kvien, Josef S Smolen, Deborah Symmons, Paul P Tak, Alan Silman It is therefore necessary to provide clear guidance about current best practice and the underlying evidence including areas of uncertainty. Ann Rheum Dis, Jan 2009, doi:10.1136/ard.2008.104406 Published Online First 15 January 2009 Arthritis Res Ther. 2020 Oct 19;22(1):247. doi: 10.1186/s13075-020-02335-4. Ann Rheum Dis, Oct 2006; 65: 1301 - 1311. Giant cell arteritis (GCA) represents the most common form of primary systemic vasculitis and is frequently associated with comorbidities related to the disease itself or induced by the treatment. Li J, Wang Y, Wang Y, Wang Y, Yang Y, Zhao J, Li M, Tian X, Zeng X. Arthritis Res Ther. Read this recommendation, Danielle M Gerlag, Karim Raza, Lisa G M van Baarsen, Elisabeth Brouwer, Christopher D Buckley, Gerd R Burmester, Cem Gabay, Anca I Catrina, Andrew P Cope, François Cornelis, Solbritt Rantapää Dahlqvist, Paul Emery, Stephen Eyre, Axel Finckh, Steffen Gay, Johanna M Hazes, Annette van der Helm-van Mil, Tom W J Huizinga, Lars Klareskog, Tore K Kvien, Cathryn Lewis, Klaus P Machold, Johan Rönnelid, Dirkjan van Schaardenburg, Georg Schett, Josef S Smolen, Sue Thomas, Jane Worthington, Paul P Tak Read this recommendation, R BM Landewé, KP Günther, C Lukas, J Braun, B Combe, P G Conaghan, K Dreinhöfer, D Fritschy, J Getty, H JL van der Heide, T K Kvien, K Machold, C Mihai, M Mosconi, R Nelissen, E Pascual, K Pavelka, M Pileckyte, W Puhl, L Punzi, W Rüther, M San-Julian, C Tudisco, R Westhovens, E Witso, and D MFM van der Heijde Epub 2019 Jun 28. A patient >50 years of age presenting with the following features should raise suspicion of GCA: 1. 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